Soderbergh first cast him in Traffic, for which he and his fellow cast members won the SAG Award for Outstanding Performance by a Cast in a Motion Picture.
He has had numerous roles on some of television’s most popular shows.
Additionally he recurs in three other television shows, as ‘Pedro’ in FX’s Louie, as ‘Christian’ in CBS’ The Good Wife and as 'Detective Anthony Nikolich’ on HBO’s Treme.
Vázquez starred on Broadway in the Tony nominated The Motherf**cker with the Hat opposite Chris Rock.
“fun House” - Filmed live at the Matrix Theater, LA, 1986. “Drinking in America” -“Alive From Off-Center, PBS, 1986. “Sex, Drugs, Rock & Roll” - Filmed live at the Wilbur Theater, Boston, 1991. In NYC he produced Nikole's Tick Parade a variety-show benefit for Lyme Disease, and the off-off-Broadway premiere of Love Sick by Kristina Poe.
“Wake Up and Smell the Coffee” – Filmed live at the Jane Street Theater, New York City, 2001. Lisa has also performed at The Public, New York Theater Workshop, The Signature, Classic Stage Company, Rattlestick, Transport Group, Stage FARM, Williamstown and The Studio Theater in D. (Helen Hayes Award, Blackbird), as well as working with the LAByrinth Theater Company where she was recently made a member.
Other film credits include The A-Team (Fox) opposite Bradley Cooper and Liam Neeson, John Sayles’ Amigo opposite Chris Cooper, Salvation Boulevard (Mandalay) opposite Jennifer Connolly, Pierce Brosnan, Marisa Tomei and Greg Kinnear, Little Fockers (Universal) with Robert De Niro and Ben Stiller, Ridley Scott’s American Gangster (Universal) alongside Russell Crowe and Denzel Washington (a 2008 SAG nominee for Outstanding Performance by a Cast in a Motion Picture), Steven Spielberg’s War of the Worlds, (Dreamworks) opposite Tom Cruise, Bad Boys II (Columbia) opposite Martin Lawrence and Will Smith, Runaway Bride (Paramount) opposite Julia Roberts and Nick of Time (Paramount) opposite Johnny Depp.